The latest hybrid Orbitrap systems, such as the Orbitrap Exploris 480 and Orbitrap Exploris 240 mass spectrometers, provide high mass resolution and accuracy over a wide mass range-including the small molecule mass range.
This can result in false identification (false negatives and false positives) of an analyte and the inability to quantitate the analytes of interest. For example, Q-TOFs are limited in their resolution at the small molecule mass range. While TOF MS systems are capable of fast full-scan data acquisition, they have limitations. During targeted analysis scans, the instrument confidently achieves confirmation and identification of residual small and large molecules. When the instrument generates full-scan HRAM data during untargeted analysis, easy identification of novel compounds and retrospective data analysis are accomplished without the need to re-run samples.
Wide performance range of high-resolution accurate-mass Quadrupole-Orbitrap MS systems ideal for targeted screening to high-throughput analysis of low-level components in complex matrices applications in biopharma for intact and native proteins, bioanalysis, forensic toxicology, clinical and translational research, environmental and food testing, metabolomics, everyday proteomics and structural biology.įor discovering, profiling and quantification of small and large molecules with versatility, selectivity, sensitivity and speed to extend limits of detection, characterization and quantitation to a broad range of applications in metabolomics, drug development, extractables and leachables, industrial environmental, multi-omics, TMT, proteomics. This extraordinary power is now available in an expanded portfolio to meet your exact analytical requirements in proteomics, metabolomics, biopharma characterization and ID, translational and clinical research, forensic toxicology, and environmental and food testing. The power of built-in intelligence, sensitivity and selectivity delivers depth of analysis, to the lowest levels with, high quantitative accuracy and precision. Next Generation advanced high-resolution accurate-mass Quadrupole-Orbitrap mass spectrometers are synonymous with record-setting performance.
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